Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 9/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874245 | 0.92 | STAT3 (0.48) | FNTAFNTBSTAT3TAS2R14CNR2 | |
| SCHEMBL7862462 | 0.91 | FNTA (0.44) | FNTAFNTBSTAT3TAS2R14CNR2 | |
| SCHEMBL7871302 | 0.89 | FNTA (0.46) | FNTAFNTBSTAT3TAS2R14PTGES | |
| SCHEMBL7862505 | 0.87 | STAT3 (0.48) | FNTAFNTBSTAT3PTGES | |
| SCHEMBL7869137 | 0.84 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL6626551 | 0.84 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL7869174 | 0.83 | MMP3 (0.45) | FNTAFNTBSTAT3TAS2R14CNR2 | |
| SCHEMBL6624997 | 0.81 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7867324 | 0.81 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL7862459 | 0.81 | FNTA (0.48) | FNTAFNTBSTAT3TAS2R14PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |