Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384809 | 0.82 | ALDH1A1 (0.35) | ALDH1A1TSHRPOLBOPRM1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL738865 | 0.81 | ALDH1A1 (0.34) | ALDH1A1TSHRPOLBOPRM1SMN1; SMN2 | |
| SCHEMBL29067375 | 0.79 | ALOX15 (0.38) | ALDH1A1ALOX15POLBOPRM1SMN1; SMN2 | |
| SCHEMBL29067373 | 0.79 | ALOX15 (0.38) | ALDH1A1ALOX15POLBOPRM1SMN1; SMN2 | |
| SCHEMBL12868735 | 0.75 | ALDH1A1 (0.39) | ALDH1A1ALOX15POLBOPRM1SMN1; SMN2 | |
| SCHEMBL7864747 | 0.75 | SMN1; SMN2 (0.35) | ALDH1A1TSHRPOLBOPRM1SMN1; SMN2 | |
| SCHEMBL1752432 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL740875 | 0.74 | ALOX15 (0.33) | ALOX15 | |
| SCHEMBL1257005 | 0.73 | OPRM1 (0.38) | ALDH1A1ALOX15POLBOPRM1SMN1; SMN2 | |
| SCHEMBL10434742 | 0.73 | ALOX15 (0.35) | ALDH1A1ALOX15POLBOPRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6218548-B1 | (TRIARYLMETHYL)AMINOSPIROPYRROLES | DAIICHI PAHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-6013806-A | ANTIBACTEIRAL | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| US-5856518-A | Production process of cyclic compound | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0829473-A1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |