Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TOP2A | P11388 | 3/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909916 | 0.81 | TOP2A (0.39) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL4419289 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL11086765 | 0.77 | TOP2A (0.46) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL378251 | 0.76 | TOP2A (0.50) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL16597500 | 0.76 | TOP2A (0.50) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL3797462 | 0.76 | CRBN (0.36) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL2903945 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL5592306 | 0.73 | TOP2A (0.48) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL10765254 | 0.72 | TOP2A (0.46) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL27618934 | 0.72 | TOP2A (0.46) | ALDH1A1TOP2ATOP2BMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119307477-A | Hydantoin enzymes and their use in hydrolyzing or preparing chiral monomer compounds | 上海合全药物研发有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-103243054-B | Carboxyethyl hydantoinase production strain and application thereof | NANJING TECH UNIVERSITY (CN) | 2014-10-29 | — | — | CN | disclosed |
| EP-1159952-A1 | COSMETICS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |