Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926635 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL11936748 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL10981379 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL22408578 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL7855502 | 0.83 | LDHA (0.41) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL8111635 | 0.82 | PKM (0.38) | SMN1; SMN2PKMHTTRECQLCES2 | |
| SCHEMBL5589408 | 0.81 | LDHA (0.37) | SMN1; SMN2PKMHCAR2DHODHESR1 | |
| SCHEMBL29927198 | 0.79 | HCAR2 (0.47) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL7855513 | 0.79 | HCAR2 (0.47) | SMN1; SMN2PKMHCAR2MEN1KMT2A | |
| SCHEMBL4636359 | 0.79 | PKM (0.34) | SMN1; SMN2PKMHCAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115259996-A | Synthetic method of transfluthrin intermediate | 浙江中欣氟材股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115259996-A | Synthetic method of transfluthrin intermediate | 浙江中欣氟材股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115259996-A | Synthetic method of transfluthrin intermediate | 浙江中欣氟材股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-6333431-B1 | ALKYLATING TETRAFLUOROBENZOIC ACID | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1114812-A1 | PROCESSES FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5744628-A | Process for the preparation of esters of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |