Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862999 | 0.79 | SMN1; SMN2 (0.42) | PKMSMN1; SMN2HTTHCAR2 | |
| SCHEMBL29926635 | 0.79 | SMN1; SMN2 (0.42) | PKMSMN1; SMN2HTTHCAR2 | |
| SCHEMBL757647 | 0.79 | CES2 (0.37) | PKMSMN1; SMN2HTT | |
| SCHEMBL8111635 | 0.75 | PKM (0.38) | PKMSMN1; SMN2HTT | |
| SCHEMBL27346255 | 0.74 | PKM (0.35) | PKMSMN1; SMN2HTT | |
| SCHEMBL11936748 | 0.74 | SMN1; SMN2 (0.41) | PKMSMN1; SMN2HTTHCAR2 | |
| SCHEMBL4617375 | 0.74 | — | — | |
| SCHEMBL10981379 | 0.73 | SMN1; SMN2 (0.39) | PKMSMN1; SMN2HTTHCAR2 | |
| SCHEMBL29175214 | 0.71 | CYP1A2 (0.38) | PKMSMN1; SMN2HTT | |
| SCHEMBL22408578 | 0.69 | SMN1; SMN2 (0.38) | PKMSMN1; SMN2HTTHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940797-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007024612-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | ARRAY BIOPHARMA INC. (US) | 2007-03-01 | — | — | WO | disclosed |