Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856497 | 0.87 | MAPT (0.50) | PPARGITGB3ITGA2BMAPTBCHE | |
| SCHEMBL7372211 | 0.87 | PPARG (0.52) | PPARGKLKB1ITGB3ITGA2BHPGD | |
| SCHEMBL7864782 | 0.85 | MAPT (0.52) | PPARGITGB3ITGA2BMAPTBCHE | |
| SCHEMBL7373439 | 0.79 | PPARG (0.70) | PPARGKLKB1ITGB3ITGA2BF10 | |
| SCHEMBL7458359 | 0.78 | PPARG (0.65) | PPARGITGB3ITGA2BF10F2 | |
| SCHEMBL7861952 | 0.77 | PPARG (0.53) | PPARGHPGDMAPTALDH1A1BCHE | |
| SCHEMBL7380584 | 0.75 | ITGB3 (0.52) | PPARGKLKB1ITGB3ITGA2BF10 | |
| SCHEMBL7377637 | 0.74 | MAPT (0.55) | PPARGITGB3ITGA2BMAPTBCHE | |
| SCHEMBL7380405 | 0.74 | F10 (0.58) | PPARGITGB3ITGA2BHPGDF10 | |
| SCHEMBL8500073 | 0.74 | MAPT (0.49) | PPARGITGB3ITGA2BHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |