Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 14/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864782 | 0.92 | MAPT (0.52) | MAPTBCHELMNASMN1; SMN2KCNK3 | |
| SCHEMBL7377637 | 0.88 | MAPT (0.55) | MAPTBCHELMNASMN1; SMN2ITGB3 | |
| SCHEMBL8500073 | 0.88 | MAPT (0.49) | MAPTBCHELMNASMN1; SMN2ITGB3 | |
| SCHEMBL7863258 | 0.87 | PPARG (0.45) | MAPTBCHEITGB3ITGA2BITGAV | |
| SCHEMBL7861952 | 0.84 | PPARG (0.53) | MAPTBCHELMNASMN1; SMN2KCNK3 | |
| SCHEMBL7380109 | 0.81 | LMNA (0.43) | BCHELMNASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL7450519 | 0.81 | PPARG (0.65) | LMNAITGB3ITGA2BHDAC6ITGAV | |
| SCHEMBL7856521 | 0.80 | PPARG (0.60) | MAPTBCHELMNASMN1; SMN2ITGB3 | |
| SCHEMBL8500043 | 0.79 | MAPT (0.57) | MAPTBCHELMNASMN1; SMN2HDAC6 | |
| SCHEMBL7863172 | 0.79 | MAPT (0.51) | MAPTBCHELMNASMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |