Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211375 | 0.81 | MYC (0.55) | LMNAKDM4ERAB9APOLBALDH1A1 | |
| SCHEMBL3075819 | 0.74 | LMNA (0.75) | LMNAHTTKDM4ERAB9AMEN1 | |
| SCHEMBL228596 | 0.73 | NR4A1 (0.47) | KDM4ERAB9AMEN1KMT2APOLB | |
| SCHEMBL6045368 | 0.73 | KDM4E (0.53) | LMNAKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL18539204 | 0.70 | NR4A1 (0.61) | LMNAKDM4EKMT2AALDH1A1ALOX15 | |
| SCHEMBL29908923 | 0.70 | ALDH1A1 (0.59) | LMNAHTTKDM4EKMT2AALDH1A1 | |
| SCHEMBL30028907 | 0.70 | ALDH1A1 (0.72) | LMNAHTTKDM4EKMT2APOLB | |
| SCHEMBL36145 | 0.70 | ALDH1A1 (0.72) | LMNAHTTKDM4EKMT2APOLB | |
| SCHEMBL28350262 | 0.69 | SOS1 (0.67) | LMNAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10513809 | 0.69 | CAMKK1 (0.52) | KDM4ERAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303542-B1 | Herbicidal 3-substituted-phenyl-1,2,3-benzotriazin-4-ones | ROHM AND HAAS COMPANY | 2001-10-16 | — | — | US | disclosed |