Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101407 | 0.86 | GRM2 (0.50) | KDM4ERAB9AKMT2AALDH1A1 | |
| SCHEMBL4525351 | 0.82 | DHODH (0.48) | KDM4EKMT2AMEN1ALDH1A1PDE10A | |
| SCHEMBL14936823 | 0.75 | KDM4E (0.61) | KDM4EKMT2AMEN1NR4A1NR4A2 | |
| SCHEMBL8324531 | 0.74 | MEN1 (0.77) | KDM4ERAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10513809 | 0.74 | CAMKK1 (0.52) | KDM4ERAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL17559805 | 0.73 | NSD2 (0.54) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7863345 | 0.73 | LMNA (0.54) | KDM4ERAB9AKMT2AMEN1NR4A1 | |
| SCHEMBL4492054 | 0.72 | ADORA2A (0.47) | KDM4ERAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL18539204 | 0.71 | NR4A1 (0.61) | KDM4EKMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL29908923 | 0.71 | ALDH1A1 (0.59) | KDM4EKMT2ANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074124-A1 | Methods of treating a disorder | IPSOL AG (LI) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074124-A1 | Methods of treating a disorder | CPT1B, CYP27A1, CLN6 | KDM4E 3776/4885RAB9A 1683/4885KMT2A 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.