Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11930064 | 0.89 | GLRA3 (0.36) | GLRA3GLRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11930063 | 0.88 | GLRA3 (0.39) | GLRA3GLRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30777257 | 0.80 | MEN1 (0.36) | GLRA3GLRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1635303 | 0.80 | MEN1 (0.36) | GLRA3GLRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5076184 | 0.79 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL29671481 | 0.77 | MEN1 (0.33) | GLRA3GLRBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28611205 | 0.77 | CYP3A4 (0.34) | GLRA3GLRB | |
| SCHEMBL27700963 | 0.76 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL10386157 | 0.75 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL14989129 | 0.75 | GLRA3 (0.46) | GLRA3GLRBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204159-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204159-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| US-6333431-B1 | ALKYLATING TETRAFLUOROBENZOIC ACID | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1114812-A1 | PROCESSES FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204159-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, OTC, AOX1 | GLRA3 3599/4885GLRB 3421/4885MEN1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.