Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394517 | 0.81 | LDHA (0.35) | SMN1; SMN2PKMHCAR2 | |
| SCHEMBL5076184 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMMEN1KMT2ATSHR | |
| SCHEMBL7863497 | 0.75 | GLRA3 (0.38) | SMN1; SMN2PKMMEN1KMT2ATSHR | |
| SCHEMBL27700963 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2PKMMEN1KMT2ATSHR | |
| SCHEMBL31542027 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ATSHRCRHBP | |
| SCHEMBL7596490 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2PKMMEN1KMT2ATSHR | |
| SCHEMBL27956970 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ATSHRCRHBP | |
| SCHEMBL5382852 | 0.70 | PKM (0.33) | SMN1; SMN2PKMHCAR2 | |
| SCHEMBL16428789 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2ATSHRCRHBP | |
| SCHEMBL10606616 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2ATSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910348-A | Reacting a polyfluoroalcoholate with a strong base | CENTRAL GLASS COMPANY, LIMITED (JP) | 1990-03-20 | — | — | US | disclosed |