Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569442 | 0.87 | LMNA (0.48) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7566806 | 0.87 | LMNA (0.48) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7784444 | 0.85 | NPC1 (0.49) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6816350 | 0.83 | LMNA (0.57) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7593322 | 0.83 | RAB9A (0.45) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7161986 | 0.82 | RAB9A (0.48) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7848325 | 0.81 | MEN1 (0.45) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7863605 | 0.80 | RAB9A (0.52) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6815341 | 0.80 | LMNA (0.46) | LMNARAB9ANPC1TLR8ALDH1A1 | |
| SCHEMBL7593650 | 0.79 | TLR8 (0.49) | LMNARAB9ANPC1TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | claimed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | claimed |
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |