SCHEMBL7863754

SCHEMBL7863754

CC(O)N(c1nc(NC(=Cc2ccccc2S(=O)(=O)O)c2ccccc2S(=O)(=O)O)nc(Nc2ccccc2)n1)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
KCNH3 Q9ULD8 7/20 0.34
ALDH1A1 P00352 1/20 0.34
TTR P02766 1/20 0.33
FABP4 P15090 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK14 Q16539 1/20 0.33
NR4A1 P22736 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.31
GPR39 O43194 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
DDX3X O00571 2/20 0.31
OGG1 O15527 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6400413 0.88 TTR (0.40) CA12CA1CA2CA9KCNH3
SCHEMBL16240781 0.85 LMNA (0.42) CA12CA1CA2CA9ALDH1A1
SCHEMBL16912708 0.84 CA1 (0.46) CA12CA1CA2CA9KCNH3
SCHEMBL8654292 0.83 CA1 (0.39) CA12CA1CA2CA9KCNH3
SCHEMBL11119443 0.80 CA1 (0.45) CA12CA1CA2CA9
SCHEMBL14759755 0.79 RHOA (0.43) CA12CA1CA2CA9KCNH3
SCHEMBL8439173 0.78 KCNH3 (0.34) CA12CA1CA2CA9KCNH3
SCHEMBL790851 0.77 ENPP2 (0.41) CA12CA1CA2CA9KCNH3
SCHEMBL4778062 0.76 CA12 (0.53) CA12CA1CA2CA9NPSR1
SCHEMBL7897023 0.76 ENPP2 (0.41) CA12CA1CA2CA9KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941299-B1 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AG (DE) 2001-08-29 EP disclosed