Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512857 | 0.93 | PTGS2 (0.40) | PTGS2CHRNA7MEN1KMT2AAOC3 | |
| SCHEMBL7861205 | 0.84 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL6513187 | 0.84 | MEN1 (0.48) | MEN1KMT2AATM | |
| SCHEMBL7863781 | 0.83 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL6516441 | 0.82 | MALT1 (0.49) | PTGS2MEN1KMT2AAOC3 | |
| SCHEMBL6517908 | 0.82 | MALT1 (0.49) | PTGS2CHRNA7MEN1KMT2AAOC3 | |
| SCHEMBL7862485 | 0.82 | GHSR (0.37) | PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL6516327 | 0.81 | PTGS2 (0.43) | PTGS2CHRNA7AOC3 | |
| SCHEMBL6519130 | 0.80 | CHRNA7 (0.54) | PTGS2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL6511614 | 0.78 | PTGS2 (0.55) | PTGS2MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | claimed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | claimed |