Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6519552 | 0.92 | PTGS2 (0.57) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL6517796 | 0.89 | PTGS2 (0.68) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL7855760 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL6511467 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL6515563 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL7861205 | 0.84 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL7863530 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL6511698 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL6516180 | 0.83 | PTGS2 (0.49) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7863776 | 0.83 | PTGS2 (0.39) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | claimed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | claimed |