Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24048190 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL1348394 | 0.87 | GAA (0.47) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL24190542 | 0.83 | KMT2A (0.50) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL9263418 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL1568667 | 0.80 | DGAT1 (0.49) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL1349347 | 0.80 | MGAM (0.47) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL1931504 | 0.80 | NLRP3 (0.55) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL22914551 | 0.80 | NR1H2 (0.50) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL5502158 | 0.79 | MEN1 (0.43) | ALDH1A1KMT2AMEN1KDM4EMGAM | |
| SCHEMBL15864186 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1KDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700399-B1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | LEPETIT SPA (IT) | 2001-10-04 | — | — | EP | disclosed |
| US-5786350-A | CONDENSATION; HYDROLYSIS; DEPROTECTING | GRUPPO LEPETIT S.P.A. (IT) | 1998-07-28 | — | — | US | disclosed |
| EP-0700399-A1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994028002-A1 | 36-DERIVATIVES OF RIFAMYCINS AND THEIR USE AS ANTIMICROBIAL AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |