SCHEMBL7863864

SCHEMBL7863864

c1ccc(NN=C(N=Nc2ccccn2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.52
TDP1 Q9NUW8 6/20 0.52
RAB9A P51151 5/20 0.52
MAPT P10636 5/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
HTT P42858 4/20 0.52
KDM4E B2RXH2 4/20 0.52
MAPK1 P28482 2/20 0.52
HSP90AA1 P07900 1/20 0.52
NPC1 O15118 4/20 0.51
KMT2A Q03164 6/20 0.46
MEN1 O00255 4/20 0.46
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
ADRA2A P08913 2/20 0.46
ADRA2B P18089 2/20 0.46
ADRA2C P18825 2/20 0.46
ALOX12 P18054 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11335174 1.00 GAA (0.52) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL9326016 0.91 KMT2A (0.52) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL11316611 0.85 MAPT (0.51) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL11335432 0.83 HTT (0.42) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL11412162 0.80 ALDH1A1 (0.61) GAATDP1RAB9AMAPTHTT
SCHEMBL11412155 0.80 ALDH1A1 (0.61) GAATDP1RAB9AMAPTHTT
SCHEMBL11331768 0.79 MAPT (0.47) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL11331775 0.79 MAPT (0.47) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL322062 0.78 RAB9A (0.73) GAATDP1RAB9AMAPTL3MBTL1
SCHEMBL491429 0.78 RAB9A (0.73) GAATDP1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0729139-B1 Optical recording medium using formazan metal complex dye TDK CORP (JP) 2001-02-07 EP disclosed
US-5604004-A Optical recording medium using formazan metal complex dye and photo-stabilizing method TDK CORPORATION (JP) 1997-02-18 US disclosed
EP-0729139-A1 Optical recording medium using formazan metal complex dye and photo-stabilizing method TDK Corporation (JP) 1996-08-28 EP disclosed
US-4292399-A Cobalt (III) complex imaging compositions having improved photographic properties EASTMAN KODAK COMPANY (US) 1981-09-29 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed