Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21610074 | 0.81 | LMNA (0.36) | ALDH1A1ANPEPADH1BADH1CADH1A | |
| SCHEMBL17088076 | 0.79 | TSHR (0.39) | ALDH1A1ADH1BADH1CADH1ACYP2C19 | |
| SCHEMBL605994 | 0.78 | — | — | |
| SCHEMBL20079280 | 0.77 | CYP2C19 (0.35) | ALDH1A1ADH1BADH1CADH1ACYP2C19 | |
| SCHEMBL19254391 | 0.76 | ADH1B (0.33) | ALDH1A1ANPEPADH1BADH1CADH1A | |
| Hydrochloric Acid SCHEMBL22400845 | 0.75 | — | — | |
| SCHEMBL7778093 | 0.75 | ADH1B (0.39) | ALDH1A1ANPEPADH1BADH1CADH1A | |
| SCHEMBL85952 | 0.74 | ANPEP (0.33) | ALDH1A1ANPEPADH1BADH1CADH1A | |
| SCHEMBL23607061 | 0.74 | — | — | |
| SCHEMBL4612569 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ALOX15ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144396-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042031-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |