Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | MGAM | O43451 | 6/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.48 |
| ▸ | SI | P14410 | 6/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478333 | 0.86 | TP53 (0.46) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL7876074 | 0.79 | ALDH1A1 (0.44) | GAARAB9AMGAMSIMGAM2 | |
| SCHEMBL7871441 | 0.79 | FGFR1 (0.64) | RAB9AALDH1A1MAPT | |
| SCHEMBL9726878 | 0.79 | MAPK1 (0.52) | TP53ALDH1A1MAPT | |
| SCHEMBL13911403 | 0.76 | KMT2A (0.50) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL12321787 | 0.75 | KMT2A (0.56) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL14397647 | 0.74 | F12 (0.49) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL3936368 | 0.74 | CA12 (0.54) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL19834327 | 0.74 | RAB9A (0.61) | GAARAB9AMGAMAMY1ASI | |
| SCHEMBL7871521 | 0.73 | PTPN1 (0.48) | RAB9ANPC1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |