Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 9/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.33 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568420 | 0.87 | FFAR1 (0.36) | KDM5AKDM5BKDM4CCYP11B1CYP11B2 | |
| SCHEMBL7570258 | 0.84 | CYP11B1 (0.34) | CTSAKDM5AKDM5BKDM4CSLC2A4 | |
| SCHEMBL8194981 | 0.82 | CTSA (0.35) | CTSAKDM5AKDM5BKDM4CSLC2A4 | |
| SCHEMBL7701993 | 0.81 | CTSA (0.33) | CTSAKDM5AKDM5BKDM4CSLC2A4 | |
| SCHEMBL8199727 | 0.81 | CTSA (0.36) | CTSAKDM5AKDM5BKDM4CADORA2B | |
| SCHEMBL7561786 | 0.78 | KDM5A (0.35) | CTSAKDM5AKDM5BKDM4CCYP11B1 | |
| SCHEMBL7561796 | 0.78 | CTSA (0.33) | CTSAKDM5AKDM5BKDM4CCYP11B1 | |
| SCHEMBL7567659 | 0.76 | KDM5A (0.35) | CTSAKDM5AKDM5BKDM4CADORA2B | |
| SCHEMBL7567637 | 0.76 | CYP11B1 (0.36) | CTSASLC2A4SLC2A8CYP11B1CYP11B2 | |
| SCHEMBL7561297 | 0.76 | TBXAS1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | disclosed |