Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501752 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNANOS3NOS1 | |
| SCHEMBL7873407 | 0.84 | SMN1; SMN2 (0.37) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7875330 | 0.84 | SMN1; SMN2 (0.37) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7859297 | 0.82 | GSK3B (0.40) | SMN1; SMN2NPC1L3MBTL1RAB9AGSK3B | |
| SCHEMBL8500531 | 0.82 | GSK3B (0.40) | SMN1; SMN2NPC1L3MBTL1RAB9AGSK3B | |
| SCHEMBL7859294 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MAPTLMNANOS3NOS1 | |
| SCHEMBL8720211 | 0.78 | GSK3B (0.50) | ALDH1A1MAPTLMNANOS1SMN1; SMN2 | |
| SCHEMBL8501552 | 0.78 | TRPA1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL8499333 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MAPTLMNANOS3NOS1 | |
| SCHEMBL7609636 | 0.78 | TRPA1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820435-B1 | METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF ALPHA-BIS-OXIMES | BASF AG (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-5929279-A | Preparation of Bisoximes | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-27 | — | — | US | disclosed |
| EP-0820435-A1 | METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF $g(a)-BIS-OXIMES | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032373-A1 | METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF α-BIS-OXIMES | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-17 | — | — | WO | disclosed |