Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356393 | 0.80 | MAOB (0.56) | FFAR1NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6190389 | 0.76 | LMNA (0.58) | NR4A1NR4A2NR4A3MAOBALOX5 | |
| SCHEMBL11204234 | 0.76 | LMNA (0.50) | NR4A1NR4A2NR4A3MAOBSRD5A2 | |
| SCHEMBL27477025 | 0.75 | FFAR1 (0.56) | FFAR1ACACBNR4A1NR4A2NR4A3 | |
| SCHEMBL11696497 | 0.75 | LMNA (0.56) | FFAR1MAOBALOX5 | |
| SCHEMBL7344629 | 0.74 | MMP12 (0.55) | FFAR1ACACBMMP12ALOX5 | |
| SCHEMBL28064096 | 0.73 | PPARG (0.57) | FFAR1NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL7908556 | 0.73 | MAOB (0.56) | FFAR1NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL9121973 | 0.72 | ACACB (0.60) | FFAR1ACACBMAOBMMP12ALOX5 | |
| SCHEMBL4818098 | 0.72 | PPARG (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | claimed |