SCHEMBL5356393

SCHEMBL5356393

CCC(c1ccc(OCc2ccccc2)cc1)C(O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.56
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
PARP10 Q53GL7 1/20 0.52
ALOX5 P09917 1/20 0.52
SRD5A2 P31213 1/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
FFAR1 O14842 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2164929 0.83 ALOX5 (0.58) MAOBNR4A1NR4A2NR4A3ALOX5
SCHEMBL7908556 0.81 MAOB (0.56) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL1923823 0.80 LMNA (0.52) PPARALMNA
SCHEMBL7167438 0.80 MAOB (0.58) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL7864559 0.80 FFAR1 (0.48) MAOBNR4A1NR4A2NR4A3ALOX5
SCHEMBL2241050 0.79 AKR1C3 (0.51) L3MBTL1FFAR1
SCHEMBL11490483 0.79 NR4A1 (0.60) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL2848849 0.79 NR4A1 (0.60) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL5722245 0.79 NR4A1 (0.60) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL6190389 0.79 LMNA (0.58) MAOBNR4A1NR4A2NR4A3ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223881-B2 Process for the preparation of new antidiabetic agents DR. REDDY'S LABORATORIES LIMITED (IN) 2007-05-29 US disclosed
US-20030125553-A1 Process for the preparation of new antidiabetic agents DR. REDDY'S LABORATORIES LIMITED 2003-07-03 US disclosed
US-6531596-B1 S(-)-2-methoxy-3-(4-(2-(phenoxazin-10-yl)methoxy) phenyl)propionic acid; benzylating p-hydroxybenzaldehyde or tyrosine; reaction with phenoxazinyl mesylate DR. REDDY'S LABORATORIES LTD. (IN) 2003-03-11 US disclosed
EP-1124808-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2001-08-22 EP disclosed
WO-2000026200-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125553-A1 Process for the preparation of new antidiabetic agents GLP1R, GPR119, SLC5A1 MAOB 2027/4885NR4A1 488/4885NR4A2 1821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.