Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306345 | 0.76 | MAPT (0.49) | ACHEKMT2AMAPTRECQLMCL1 | |
| SCHEMBL4301706 | 0.76 | KDM4E (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL2139179 | 0.75 | KDM4E (0.54) | GAAKMT2AMAPTMEN1APP | |
| SCHEMBL12479627 | 0.75 | MEN1 (0.52) | MGAMGAASIMGAM2TXNRD1 | |
| SCHEMBL7866207 | 0.73 | PNMT (0.38) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL11366878 | 0.72 | MGAM (0.40) | MGAMGAASIMGAM2TXNRD1 | |
| SCHEMBL10426653 | 0.72 | PDE10A (0.49) | MGAMGAASIMGAM2TXNRD1 | |
| SCHEMBL31122218 | 0.72 | PDE10A (0.49) | MGAMGAASIMGAM2TXNRD1 | |
| Fluorene SCHEMBL27883247 | 0.69 | ALDH1A1 (0.53) | ACHEKMT2AMAPTRECQLMCL1 | |
| SCHEMBL4920165 | 0.69 | ALDH1A1 (0.50) | TXNRD1TXNRD3TXNRD2PDE10AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300502-B1 | Multi-armed chromophores with very large two-photon absorption cross-sections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2001-10-09 | — | — | US | disclosed |