Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.74 |
| ▸ | HTR6 | P50406 | 4/20 | 0.74 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | HTR5A | P47898 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244966 | 0.85 | HTR1D (1.00) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL7433474 | 0.84 | HTR1D (0.97) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL7806663 | 0.82 | HTR1D (0.82) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| Cyanide SCHEMBL28561862 | 0.82 | HTR1D (0.92) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL8555235 | 0.78 | HTR1D (0.76) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL4231080 | 0.77 | HTR1D (0.74) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL23226374 | 0.76 | AKR1C2 (0.61) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL11374190 | 0.75 | ALDH1A1 (0.78) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL5766124 | 0.75 | HTR6 (1.00) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL29633021 | 0.75 | HTR6 (1.00) | HTR1DHTR6HTR7HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055107-A2 | AROMATIC AMINES AND AMIDES ACTING ON THE MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |