Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593043 | 0.87 | HDAC4 (0.42) | KDM5AERN1GPBAR1MAPT | |
| SCHEMBL7860205 | 0.86 | MEN1 (0.42) | KMT2AMEN1KDM5AKDM4ELMNA | |
| SCHEMBL7865102 | 0.85 | MEN1 (0.38) | KMT2AMEN1KDM5AKDM4ELMNA | |
| SCHEMBL7861641 | 0.84 | TSHR (0.38) | KMT2AMEN1KDM4ELMNANPC1 | |
| SCHEMBL7818937 | 0.83 | PTGS2 (0.44) | KMT2AMEN1PGRPTGS2KDM5A | |
| SCHEMBL6202118 | 0.83 | MEN1 (0.43) | KMT2AMEN1PGRPTGS2KDM5A | |
| SCHEMBL7861633 | 0.82 | KDM4E (0.37) | KDM5AKDM4ENPC1ERN1MAPT | |
| SCHEMBL7558786 | 0.80 | MAPT (0.41) | KMT2AMEN1KDM5AKDM4ERXFP1 | |
| SCHEMBL7556667 | 0.80 | HSD17B1 (0.34) | KMT2AMEN1KDM5AKDM4ERXFP1 | |
| SCHEMBL15200742 | 0.78 | KMT2A (0.43) | KMT2AMEN1PGRPTGS2KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003992-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |