Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 10/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860408 | 1.00 | MMP2 (0.51) | MMP2MMP12MMP9MMP3MMP13 | |
| SCHEMBL7862695 | 0.96 | MMP2 (0.50) | MMP2MMP12MMP9MMP3MMP13 | |
| SCHEMBL10021381 | 0.96 | MMP2 (0.50) | MMP2MMP12MMP9MMP3MMP13 | |
| SCHEMBL7861855 | 0.90 | MMP2 (0.44) | MMP2MMP12MMP9MMP3MMP13 | |
| SCHEMBL7860511 | 0.85 | MMP2 (0.47) | MMP2MMP12MMP9MMP3MMP13 | |
| SCHEMBL7860406 | 0.83 | THRA (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7860432 | 0.83 | THRA (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7860409 | 0.83 | THRA (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7854961 | 0.83 | THRA (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL7854992 | 0.83 | MMP2 (0.52) | MMP2MMP9CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923529-B1 | SUBSTITUTE 4-ARYLBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-09-19 | — | — | EP | disclosed |
| US-5863915-A | ENZYME INHIBITORS FOR BONES AND JOINTS | BAYER CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |