Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810116 | 0.86 | L3MBTL1 (0.57) | L3MBTL1NLRP3KMT2AMEN1GAA | |
| SCHEMBL1810118 | 0.86 | L3MBTL1 (0.57) | L3MBTL1NLRP3KMT2AMEN1GAA | |
| SCHEMBL26722457 | 0.85 | NLRP3 (0.58) | NLRP3KMT2AMEN1GAAMAPT | |
| SCHEMBL16387340 | 0.84 | NLRP3 (0.53) | NLRP3KMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL15700203 | 0.83 | NLRP3 (0.56) | NLRP3KMT2AMEN1GAAMAPT | |
| SCHEMBL14756765 | 0.83 | NLRP3 (0.56) | NLRP3KMT2AMEN1GAAMAPT | |
| SCHEMBL21788586 | 0.83 | NLRP3 (0.56) | NLRP3KMT2AMEN1GAAMAPT | |
| SCHEMBL15985297 | 0.83 | NLRP3 (0.59) | NLRP3MAPT | |
| SCHEMBL12377475 | 0.83 | CA1 (0.60) | NLRP3KMT2AMEN1TRPV1ESRRG | |
| SCHEMBL16387330 | 0.81 | HDAC1 (0.55) | NLRP3KMT2AMEN1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741734-B1 | PHENYLBORONIC ACID COMPLEXES | PROLINX INC (US) | 2001-04-04 | — | — | EP | disclosed |
| US-5677431-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5623055-A | Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation | PROLINX, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5594111-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0741734-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020591-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1995-08-03 | — | — | WO | disclosed |