Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387340 | 0.84 | NLRP3 (0.53) | CA1CA2NLRP3TERTMEN1 | |
| SCHEMBL6353539 | 0.83 | RAB9A (0.63) | NLRP3MEN1KMT2AALDH1A1POLB | |
| SCHEMBL8622297 | 0.83 | NLRP3 (0.58) | NLRP3MEN1KMT2ATRPV1ESRRG | |
| SCHEMBL7744399 | 0.83 | NLRP3 (0.58) | CA1CA2NLRP3MEN1KMT2A | |
| SCHEMBL14756770 | 0.83 | NLRP3 (0.58) | CA1CA2NLRP3MEN1KMT2A | |
| SCHEMBL7865481 | 0.83 | L3MBTL1 (0.61) | CA1CA2NLRP3MEN1KMT2A | |
| SCHEMBL16387330 | 0.82 | HDAC1 (0.55) | NLRP3MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL19747848 | 0.82 | CA1 (0.67) | CA1CA2TERTMEN1KMT2A | |
| SCHEMBL1303751 | 0.81 | TRPV1 (0.51) | CA1CA2NLRP3TRPV1ESRRG | |
| SCHEMBL1810118 | 0.81 | L3MBTL1 (0.57) | NLRP3MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989625-B2 | Thienopyridines | MERCK PATENT GMBH (DE) | 2011-08-02 | — | — | US | disclosed |
| US-7989625-B2 | Thienopyridines | MERCK PATENT GMBH (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20100048558-A1 | THIENOPYRIDINES | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20100048558-A1 | THIENOPYRIDINES | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048558-A1 | THIENOPYRIDINES | HSP90AB2P, HSP90AB1, HSP90AA1 | CA1 4694/4885CA2 2279/4885NLRP3 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.