Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428472 | 0.86 | MAPT (0.59) | MAPTGAAKDM4EATMRORC | |
| SCHEMBL2912192 | 0.82 | MAPT (0.59) | MAPTGAAKDM4EATMRAB9A | |
| SCHEMBL110681 | 0.80 | ALDH1A1 (0.52) | MAPTGAAKDM4EL3MBTL1MEN1 | |
| SCHEMBL29534931 | 0.80 | ALDH1A1 (0.52) | MAPTGAAKDM4EL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL15486482 | 0.79 | MAPT (0.53) | MAPTGAAKDM4EATML3MBTL1 | |
| SCHEMBL7865742 | 0.78 | RORC (0.52) | MAPTGAAKDM4EERN1ATM | |
| Benzene SCHEMBL28800866 | 0.77 | CYP1A2 (0.50) | MAPTGAAKDM4EL3MBTL1HTT | |
| SCHEMBL77110 | 0.77 | MEN1 (0.57) | MAPTGAAKDM4ERAB9AMEN1 | |
| SCHEMBL29393582 | 0.77 | MEN1 (0.57) | MAPTGAAKDM4ERAB9AMEN1 | |
| SCHEMBL1159205 | 0.76 | GAA (0.96) | MAPTGAAKDM4EATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |