Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534931 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EUSP2MAPTGAA | |
| Hydrochloric Acid SCHEMBL15486482 | 0.98 | MAPT (0.53) | ALDH1A1KDM4EUSP2MAPTGAA | |
| Benzene SCHEMBL28800866 | 0.96 | CYP1A2 (0.50) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL109131 | 0.82 | MAPT (0.55) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL7937909 | 0.82 | TUBB1 (0.41) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL212391 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL15514306 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL29389101 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL7186654 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EUSP2MAPTGAA | |
| SCHEMBL21904888 | 0.81 | TDP1 (0.52) | ALDH1A1KDM4EUSP2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039160-A | Synthetic method for preparing 3-bromo-4-iodoanisole with high selectivity | 江苏阿尔法药业股份有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-108685921-A | A kind of application of the quinoline of N isosteres iridin in medicines resistant to liver cancer | 广州大学 | 2018-10-23 | — | — | CN | claimed |
| CN-108218839-A | A kind of preparation method of antitumor drug AZD9291 | 上药康丽（常州）药业有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-106604918-A | Polycyclic hERG activators | 诺华股份有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-102199099-A | Method for preparing 3-bromo-4-methoxyaniline | UNIV CHANGZHOU | 2011-09-28 | — | — | CN | claimed |
| CN-122036709-A | Halogenated anisole-containing side chain dithienyl pyrrole monomer, conjugated polymer, preparation method and application | 南阳师范学院 | 2026-05-15 | — | — | CN | disclosed |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20260042743-A1 | SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES | COUNCIL SCIENT IND RES (IN) | 2026-02-12 | — | — | US | disclosed |
| US-20260028316-A1 | Biphenyl and Phenylpyridine Compounds | PFIZER INC. (US) | 2026-01-29 | — | — | US | disclosed |
| US-12522597-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| US-12509460-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-12497398-B2 | Potent and selective covalent inhibitors of serine-arginine protein kinase (SRPK) 1 and SRPK2 and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| WO-1998001450-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |
| WO-1997049710-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997030055-A1 | SPIRO-KETAL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997019084-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| EP-0733048-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015954-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-06-15 | — | — | WO | disclosed |
| EP-0637300-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993020055-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509460-B2 | Methods and compositions for modulating splicing | SF3B1, RTCB, RBM17 | ALDH1A1 3032/4885KDM4E 2036/4885USP2 3083/4885 |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | HTR2C, HTR1A, HTR2A | ALDH1A1 873/4885KDM4E 4301/4885USP2 3497/4885 |
| US-12497398-B2 | Potent and selective covalent inhibitors of serine-arginine protein kinase (SRPK) 1 and SRPK2 and uses thereof | SRPK1, SRPK2, SRPK3 | ALDH1A1 4615/4885KDM4E 1885/4885USP2 1345/4885 |
| US-20260028316-A1 | Biphenyl and Phenylpyridine Compounds | KAT2B, KAT2A, KAT6A | ALDH1A1 1348/4885KDM4E 57/4885USP2 1831/4885 |
| US-20260042743-A1 | SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES | ACE2, SARS1, NR3C2 | ALDH1A1 2751/4885KDM4E 3426/4885USP2 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.