SCHEMBL7865853

SCHEMBL7865853

COc1ccc(COC(=O)Cc2ccccc2N)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
KDM4E B2RXH2 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ATM Q13315 1/20 0.48
FABP7 O15540 1/20 0.48
FABP5 Q01469 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
MAPK1 P28482 1/20 0.47
KLK7 P49862 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
HPGD P15428 1/20 0.46
MCL1 Q07820 1/20 0.46
HTT P42858 1/20 0.45
P2RX4 Q99571 1/20 0.45
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15412884 0.86 MAPT (0.48) ALDH1A1ATMFABP7FABP5L3MBTL1
SCHEMBL20126456 0.85 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2HSD17B10L3MBTL1MAPK1
SCHEMBL3727812 0.84 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL10049359 0.82 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL1171464 0.81 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL11684699 0.81 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL29024631 0.77 RAB9A (0.63) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL11631661 0.77 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KDM4EHSD17B10L3MBTL1
SCHEMBL3732393 0.76 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM
SCHEMBL28250075 0.76 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2KDM4EHSD17B10ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300495-B1 REACTING ORGANIC AMINE SALT OF CLAVULANIC ACID WITH METAL SALT IN LIQUID MEDIUM OF FLUORINATED AND/OR CHLORINATED HYDROCARBON SMITHKLINE BEECHAM P.L.C. (GB) 2001-10-09 US disclosed