Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.34 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301113 | 0.86 | — | — | |
| SCHEMBL1501596 | 0.86 | — | — | |
| SCHEMBL381512 | 0.86 | — | — | |
| SCHEMBL28401151 | 0.84 | ALDH1A1 (0.45) | TSHRTET2ALDH1A1CHRM1ADRA1A | |
| Succinic Acid SCHEMBL3145429 | 0.77 | FFAR3 (0.48) | TSHRTET2ALDH1A1HDAC1HDAC2 | |
| SCHEMBL11116390 | 0.76 | GPR84 (0.70) | ACACBACACAGPR84FFAR1HSPD1 | |
| Maleic Acid SCHEMBL19611146 | 0.76 | HCAR2 (0.42) | TSHRTET2ALDH1A1FDPS | |
| Cadaverine Tartrate SCHEMBL2158124 | 0.75 | TSHR (0.67) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| Lactic Acid SCHEMBL28127623 | 0.75 | TP53 (0.44) | TET2CA2MAPK1ACACBACACA | |
| SCHEMBL9082385 | 0.74 | TET2 (0.38) | TSHRTET2ALDH1A1CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161518-A2 | TOWELETTE PRODUCT | UNILEVER PLC (GB) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000056271-A2 | TOWELETTE PRODUCT | UNILEVER PLC (GB) | 2000-09-28 | — | — | WO | disclosed |