Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869835 | 0.84 | MAPT (0.49) | MAPTLMNALIPEPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7868843 | 0.84 | PTGDR2 (0.45) | MAPTLMNALIPEPOLBKMT2A | |
| SCHEMBL7869785 | 0.83 | HRH3 (0.49) | MAPTLMNALIPEPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7862079 | 0.83 | MAPT (0.48) | MAPTLMNALIPEPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7866529 | 0.82 | HRH3 (0.48) | MAPTLMNALIPEPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7862065 | 0.82 | MAPT (0.49) | MAPTLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL7866988 | 0.78 | ENPP3 (0.60) | MAPTLMNAPOLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7869908 | 0.77 | NAMPT (0.43) | ABL1MAPTLMNAPOLBKMT2A | |
| SCHEMBL7866937 | 0.77 | ACACB (0.45) | ABL1MAPTLMNAPOLBKMT2A | |
| SCHEMBL7869933 | 0.76 | KMT2A (0.58) | MAPTLMNAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |