Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23422467 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2TSHRALDH1A1GLAMAPK1 | |
| SCHEMBL3863960 | 0.75 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL27532029 | 0.75 | LMNA (0.41) | KMT2ARECQLALDH1A1 | |
| SCHEMBL547492 | 0.74 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2TSHRALDH1A1GLA | |
| SCHEMBL16858004 | 0.73 | NPSR1 (0.41) | KMT2ASMN1; SMN2TSHRALDH1A1GLA | |
| SCHEMBL547805 | 0.73 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2TSHRALDH1A1GLA | |
| SCHEMBL9949399 | 0.72 | TRPM8 (0.44) | NR1H2NR1H3SMN1; SMN2MAPK1 | |
| SCHEMBL7639218 | 0.72 | NPSR1 (0.40) | KMT2ASMN1; SMN2TSHRALDH1A1GLA | |
| SCHEMBL8597741 | 0.70 | NPSR1 (0.39) | KMT2ASMN1; SMN2TSHRALDH1A1GLA | |
| SCHEMBL11329376 | 0.70 | KMT2A (0.46) | KMT2AGAATSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300495-B1 | REACTING ORGANIC AMINE SALT OF CLAVULANIC ACID WITH METAL SALT IN LIQUID MEDIUM OF FLUORINATED AND/OR CHLORINATED HYDROCARBON | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-10-09 | — | — | US | disclosed |
| EP-0804441-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022296-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-25 | — | — | WO | disclosed |