Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773597 | 0.91 | KMT2A (0.50) | LMNAKMT2AALDH1A1GAACYP1A2 | |
| SCHEMBL7862213 | 0.87 | KMT2A (0.69) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL7870795 | 0.84 | ALDH1A1 (0.71) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL7874122 | 0.84 | KMT2A (0.58) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL7862198 | 0.84 | LMNA (0.55) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL23703133 | 0.84 | KMT2A (0.73) | LMNAKMT2AALDH1A1GAACYP1A2 | |
| SCHEMBL28897130 | 0.84 | KMT2A (0.53) | LMNAKMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28244926 | 0.84 | LMNA (0.65) | LMNAKMT2AALDH1A1GAACYP1A2 | |
| SCHEMBL7866944 | 0.83 | LMNA (0.53) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL27466607 | 0.82 | LMNA (0.63) | LMNAKMT2AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |