Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862198 | 0.87 | LMNA (0.55) | KMT2ALMNAALDH1A1GAAKDM4E | |
| SCHEMBL7870795 | 0.87 | ALDH1A1 (0.71) | KMT2ALMNAALDH1A1GAAKDM4E | |
| SCHEMBL7874122 | 0.87 | KMT2A (0.58) | KMT2ALMNAALDH1A1GAAKDM4E | |
| SCHEMBL7867055 | 0.87 | LMNA (0.55) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL28244926 | 0.87 | LMNA (0.65) | KMT2ALMNAALDH1A1GAAKDM4E | |
| SCHEMBL7866944 | 0.86 | LMNA (0.53) | KMT2ALMNAALDH1A1GAAKDM4E | |
| SCHEMBL7874157 | 0.85 | KMT2A (0.71) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL27466607 | 0.84 | LMNA (0.63) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL14578750 | 0.83 | LMNA (0.61) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7870173 | 0.83 | ALDH1A1 (0.68) | KMT2ALMNAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| CN-108276313-A | A method of synthesizing (S) -2- p-toluenesulfonyl ethyl propionates using micro flow field technology continuous flow | 东南大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-102786490-A | Synthesis method of fenoxaprop | ANHUI FENGLE AGROCHEMICAL CO | 2012-11-21 | — | — | CN | disclosed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |