Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021256 | 0.90 | TSHR (0.39) | TSHRALDH1A1HPGD | |
| SCHEMBL671633 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL31174545 | 0.83 | TSHR (0.44) | TSHRALDH1A1HPGDTP53CYP3A4 | |
| SCHEMBL27586927 | 0.80 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL7867278 | 0.80 | TSHR (0.42) | TSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL9242015 | 0.80 | TSHR (0.42) | TSHRALDH1A1HPGDTP53CYP3A4 | |
| SCHEMBL4915952 | 0.80 | ALDH1A1 (0.38) | TSHRALDH1A1HPGDTP53CYP3A4 | |
| SCHEMBL671634 | 0.79 | TSHR (0.41) | TSHRALDH1A1HPGDTP53CYP3A4 | |
| SCHEMBL22245968 | 0.78 | TSHR (0.40) | TSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL4863709 | 0.77 | TSHR (0.54) | TSHRALDH1A1HPGDTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | claimed |
| EP-0875509-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5932725-A | PHOTOCHROMIC; E.G., 3,3-BIS(3-FLUORO-4-METHOXYPHENYL)-6-MORPHOLINO-3H-BENZO(F)-CHR OMENE | TOKUYAMA CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0875509-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 1998-11-04 | — | — | EP | disclosed |