Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870399 | 0.85 | SOS2 (0.68) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL14527119 | 0.84 | SOS2 (0.59) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL5648360 | 0.84 | LTA4H (0.69) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL14527174 | 0.84 | SOS2 (0.59) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL5481516 | 0.84 | LTA4H (0.69) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL14527120 | 0.84 | SOS2 (0.59) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL5480477 | 0.83 | TSHR (0.53) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL5480473 | 0.83 | TSHR (0.53) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL31688533 | 0.83 | KMT2A (0.56) | SOS2HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL14527122 | 0.83 | SOS2 (0.58) | SOS2HTR2AHTR2CHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801059-B1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5817689-A | ADRENERGIC RECEPTOR-STIMULATING AGENT, OBESITY, DIABETES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0801059-A1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-10-15 | — | — | EP | disclosed |