Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.69 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.69 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648360 | 1.00 | LTA4H (0.69) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| Oxalic Acid SCHEMBL7571181 | 0.94 | LTA4H (0.62) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| SCHEMBL6617826 | 0.88 | LTA4H (0.70) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| SCHEMBL5859936 | 0.85 | LTA4H (0.66) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| SCHEMBL5859941 | 0.85 | LTA4H (0.66) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| SCHEMBL837541 | 0.84 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3ADRB1 | |
| SCHEMBL837542 | 0.84 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3ADRB1 | |
| SCHEMBL7867296 | 0.84 | SOS2 (0.65) | LTA4HPLA2G2ATRPM8SOS2ADRB3 | |
| SCHEMBL30579433 | 0.82 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3SLC6A4 | |
| SCHEMBL5167328 | 0.82 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217724-B2 | Indole, indazole, and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20060063762-A1 | Indole indazole and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| CN-1675180-A | Indole, indazole, and benzazole derivative | SUMITOMO PHARMA (JP) | 2005-09-28 | — | — | CN | disclosed |
| EP-1514869-A1 | INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-03-16 | — | — | EP | disclosed |
| CN-1433403-A | Solid pharmaceutical preparation | DAINIPPON PHARMAECUTICAL CO LT (JP) | 2003-07-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063762-A1 | Indole indazole and benzazole derivative | ADRB3, ADRA2C, ADRB2 | LTA4H 3017/4885PLA2G2A 3711/4885TRPM8 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.