Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874393 | 0.92 | NPSR1 (0.57) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7867583 | 0.91 | NPSR1 (0.58) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7867528 | 0.89 | KMT2A (0.62) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7872611 | 0.89 | NPSR1 (0.73) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7874392 | 0.87 | NPSR1 (0.60) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7874397 | 0.83 | ALDH1A1 (0.56) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7867590 | 0.82 | NPSR1 (0.71) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7867554 | 0.81 | TAS1R3 (0.56) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7876133 | 0.80 | NPSR1 (0.71) | KMT2ASMN1; SMN2NPSR1LMNAMAPT | |
| SCHEMBL7872607 | 0.80 | TAS1R3 (0.53) | KMT2ASMN1; SMN2NPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-B1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORP (US) | 2001-09-26 | — | — | EP | claimed |