Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874408 | 0.88 | NPSR1 (0.62) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7867548 | 0.87 | NPSR1 (0.51) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7867322 | 0.83 | KMT2A (0.63) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7874393 | 0.81 | NPSR1 (0.57) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7867583 | 0.80 | NPSR1 (0.58) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7994381 | 0.76 | NPSR1 (0.46) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL24175859 | 0.73 | TAS1R3 (0.68) | ALDH1A1NPSR1SMN1; SMN2LMNATAS1R3 | |
| SCHEMBL21274338 | 0.73 | TAS1R3 (0.61) | ALDH1A1SMN1; SMN2LMNATAS1R3TAS1R1 | |
| SCHEMBL21274340 | 0.73 | TAS1R3 (0.61) | ALDH1A1SMN1; SMN2LMNATAS1R3TAS1R1 | |
| SCHEMBL7867528 | 0.72 | KMT2A (0.62) | ALDH1A1NPSR1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-B1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORP (US) | 2001-09-26 | — | — | EP | claimed |