Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574662 | 0.93 | CA1 (0.40) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL7870343 | 0.93 | RAB9A (0.42) | ALDH1A1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL7862836 | 0.91 | ALDH1A1 (0.47) | ALDH1A1CA1CA2OPRM1OPRD1 | |
| SCHEMBL7870462 | 0.90 | NPC1 (0.39) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL9574894 | 0.89 | SMN1; SMN2 (0.42) | ALDH1A1CA1CA2CA7OPRM1 | |
| SCHEMBL9018356 | 0.89 | ALDH1A1 (0.41) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL7871670 | 0.88 | CA1 (0.41) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL7869411 | 0.87 | RAB9A (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2P4HTM | |
| SCHEMBL8869704 | 0.87 | P4HTM (0.45) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL7871649 | 0.87 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |