Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479592 | 0.78 | KDM4E (0.39) | L3MBTL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6043188 | 0.76 | HDAC3 (0.59) | MAPTL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7867709 | 0.76 | RARG (0.37) | TDP1RARGKDM4ETSHRPTPN1 | |
| SCHEMBL1496808 | 0.76 | ALDH1A1 (0.50) | MAPTL3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL16016038 | 0.73 | TSHR (0.41) | MAPTL3MBTL1KDM4ETSHRRAB9A | |
| SCHEMBL12329804 | 0.72 | KDM4E (0.38) | MAPTKDM4ETSHRALDH1A1GAA | |
| SCHEMBL1496779 | 0.72 | ALDH1A1 (0.48) | MAPTL3MBTL1KDM4ETSHRRAB9A | |
| SCHEMBL5837433 | 0.71 | PTPN1 (0.44) | MAPTTDP1L3MBTL1HDAC3HDAC4 | |
| SCHEMBL16035002 | 0.70 | HDAC3 (0.38) | MAPTTDP1L3MBTL1HDAC3HDAC4 | |
| SCHEMBL1050558 | 0.70 | ALDH1A1 (0.49) | MAPTTDP1L3MBTL1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035915-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-22 | — | — | WO | disclosed |