Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 4/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867705 | 0.76 | MAPT (0.39) | RARGTSHRPTPN1KDM4EALDH1A1 | |
| SCHEMBL28476894 | 0.72 | TSHR (0.50) | TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL28519625 | 0.70 | TSHR (0.54) | TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL6479592 | 0.66 | KDM4E (0.39) | RARGKDM4EALDH1A1F2ELANE | |
| SCHEMBL17719425 | 0.66 | EGFR (0.37) | TSHRKDM4EALDH1A1TDP1F2 | |
| SCHEMBL28384052 | 0.66 | TSHR (0.42) | TSHRPTPN1KDM4EALDH1A1TDP1 | |
| SCHEMBL28102658 | 0.65 | TSHR (0.51) | TSHRKDM4EALDH1A1 | |
| SCHEMBL28378193 | 0.64 | LMNA (0.52) | TSHRKDM4EALDH1A1TDP1F2 | |
| SCHEMBL6043188 | 0.64 | HDAC3 (0.59) | TSHRKDM4EALDH1A1 | |
| SCHEMBL27748326 | 0.64 | TSHR (0.36) | TSHRKDM4EALDH1A1TDP1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035915-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-22 | — | — | WO | disclosed |