Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674250 | 0.86 | HTR6 (0.77) | HTR6SLC6A4 | |
| SCHEMBL7485600 | 0.83 | HTR6 (0.55) | HTR6SLC6A4 | |
| SCHEMBL7483404 | 0.82 | HTR6 (0.54) | HTR6SLC6A4 | |
| SCHEMBL7490646 | 0.82 | HTR6 (0.59) | HTR6SLC6A4 | |
| SCHEMBL9463098 | 0.82 | HTR6 (0.49) | HTR6SLC6A4 | |
| SCHEMBL7485451 | 0.82 | HTR6 (0.57) | HTR6SLC6A4 | |
| SCHEMBL9463103 | 0.81 | HTR6 (0.50) | HTR6SLC6A4 | |
| SCHEMBL7484100 | 0.80 | HTR6 (0.54) | HTR6SLC6A4 | |
| SCHEMBL9463347 | 0.79 | HTR6 (0.58) | HTR6SLC6A4 | |
| SCHEMBL7482946 | 0.78 | HTR6 (0.59) | HTR6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077213-A2 | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6046215-A | A PIPERIDINYLBENZOTHIOPHENES USEFUL FOR TRATING BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| US-5846982-A | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |