SCHEMBL9463103

SCHEMBL9463103

CN1CC=C(c2cn(C(=O)c3nccs3)c3ccc(F)cc23)CC1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 9/20 0.50
SLC6A4 P31645 1/20 0.44
CCNT1 O60563 1/20 0.38
CDK9 P50750 1/20 0.38
SCN9A Q15858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7483404 0.83 HTR6 (0.54) HTR6SLC6A4
SCHEMBL7868014 0.81 HTR6 (0.56) HTR6SLC6A4
SCHEMBL4674250 0.81 HTR6 (0.77) HTR6SLC6A4
SCHEMBL7485600 0.78 HTR6 (0.55) HTR6SLC6A4
SCHEMBL7490646 0.77 HTR6 (0.59) HTR6SLC6A4
SCHEMBL7485451 0.77 HTR6 (0.57) HTR6SLC6A4
SCHEMBL9463098 0.77 HTR6 (0.49) HTR6SLC6A4
SCHEMBL7484100 0.75 HTR6 (0.54) HTR6SLC6A4
SCHEMBL7482946 0.74 HTR6 (0.59) HTR6SLC6A4
SCHEMBL7484905 0.72 HTR6 (0.83) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE34299-E Psychological disorders, neuroleptic agents, analgesics H. LUNDBECK A/S (DK) 1993-06-29 US disclosed