SCHEMBL7868083

SCHEMBL7868083

Cc1cccc(-c2ccccc2S(=O)(=O)O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
PGAM1 P18669 1/20 0.42
ELANE P08246 3/20 0.42
MYC P01106 2/20 0.42
TRPA1 O75762 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
CTSG P08311 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 2/20 0.38
GAA P10253 2/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
KDM4A O75164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886759 0.85 MYC (0.47) PGAM1MYCHPGDTTRBRD4
SCHEMBL28227958 0.84 MYC (0.43) PGAM1MYCTRPA1KMT2AGAA
SCHEMBL21084 0.83 ALDH1A1 (0.54) ALDH1A1PGAM1ELANEMYCTRPA1
SCHEMBL4163086 0.81 NFKB1 (0.45) ALDH1A1PGAM1MYCKDM4EHPGD
SCHEMBL28396990 0.81 ALDH1A1 (0.52) ALDH1A1PGAM1ELANEMYCTRPA1
Hydrochloric Acid SCHEMBL9814070 0.81 ALDH1A1 (0.52) ALDH1A1PGAM1ELANEMYCTRPA1
Water SCHEMBL3630768 0.81 ALDH1A1 (0.52) ALDH1A1PGAM1ELANEMYCTRPA1
Ammonia Solution, Strong SCHEMBL7744383 0.81 ALDH1A1 (0.52) ALDH1A1PGAM1ELANEMYCTRPA1
SCHEMBL458284 0.80 SMN1; SMN2 (0.48) PGAM1MYCKDM4ECYP1A2KMT2A
Formaldehyde SCHEMBL958921 0.79 ALDH1A1 (0.50) ALDH1A1PGAM1ELANEMYCTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303562-B1 ALKYLATING HYDROXYPHENYLBENZENESULFINIC/SULFONIC ACID COMPOUND WITH ALKENE OR SUBSTITUTED ALKENE TO FORM ALKYLATED PRODUCT ENCHIRA BIOTECHNOLOGY CORPORATION 2001-10-16 US disclosed
WO-2000042005-A1 COMPOSITIONS COMPRISING 2-(2-HYDROXYPHENYL) BENZENESULFINATE AND ALKYL-SUBSTITUTED DERIVATIVES THEREOF ENERGY BIOSYSTEMS CORPORATION (US) 2000-07-20 WO disclosed