Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 3/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803701 | 0.89 | CYP2C9 (0.44) | CYP2C9TSHRPTPN1PGD | |
| SCHEMBL30899162 | 0.83 | CYP2C9 (0.38) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL372294 | 0.83 | PGD (0.46) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL891729 | 0.82 | PGD (0.47) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL2229219 | 0.80 | PTPN1 (0.39) | PTPN1PGDPGK1PGK2 | |
| SCHEMBL28526665 | 0.77 | CYP2C9 (0.35) | CYP2C9TSHRPTPN1PGD | |
| SCHEMBL37330 | 0.77 | PGD (0.43) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL9736405 | 0.77 | PGD (0.43) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL4959398 | 0.77 | PGD (0.43) | CYP2C9TSHRPTPN1PGDPGK1 | |
| SCHEMBL8854308 | 0.76 | PTPN1 (0.41) | PTPN1PGDPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135471-A1 | PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034448-A1 | PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-06-15 | — | — | WO | disclosed |