SCHEMBL2229219

SCHEMBL2229219

CC(=O)[C@@H](O)[C@@H](CO)OP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
PGD P52209 3/20 0.33
SMPD1 P17405 3/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891729 0.82 PGD (0.47) PTPN1PGDPGK1PGK2
SCHEMBL7868485 0.80 CYP2C9 (0.38) PTPN1PGDPGK1PGK2
SCHEMBL8854308 0.76 PTPN1 (0.41) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL4611932 0.74 PGD (0.33) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL28033517 0.74 PTPN1 (0.43) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL2216482 0.74 PTPN1 (0.43) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL8139325 0.74 SMPD1 (0.36) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL7803701 0.73 CYP2C9 (0.44) PTPN1PGD
SCHEMBL3371759 0.72 PTPN1 (0.36) PTPN1PGDSMPD1PGK1PGK2
SCHEMBL6350847 0.72 PTPN1 (0.37) PTPN1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461322-B2 Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-11 US disclosed
US-20110185450-A1 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 US disclosed
US-7842855-B2 Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-30 US disclosed
EP-1135471-B1 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DU PONT (US) 2009-05-27 EP disclosed
US-20080229446-A1 Expression vector comprising nucleotide sequences coding isomerase for use in generating plants with enhanced isoprenoid biosynthesis E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-18 US disclosed
US-7381541-B2 Methods for producing animal feed preparations with astaxanthin-containing plants or parts of plants of the genus Tagetes SUNGENE GMBH & CO. KGAA (DE) 2008-06-03 US disclosed
US-20080060096-A1 Novel Ketolases and Method for Producing Ketocarotinoids SUNGENE GMBH (DE) 2008-03-06 US disclosed
US-7282359-B2 Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-10-16 US disclosed
US-7195887-B2 Rice 1-deoxy-D-xylulose 5-phosphate synthase and DNA encoding thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-27 US disclosed
US-20060272056-A1 Plant 1-deoxy-D-xylulose 5-phosphate synthase CAHOON REBECCA E 2006-11-30 US disclosed
US-20060194274-A1 Method for producing ketocarotinoids in genetically modified, non-human organisms SUNGENE GMBH (DE) 2006-08-31 US disclosed
US-20060031963-A1 Method for the production of ketocarotinoids in flower petals on plants SUNGENE GMBH & CO. KGAA (DE) 2006-02-09 US disclosed
US-20050281909-A1 Use of astaxanthin-containing plants or parts of plants of the genus tagetes as feedstuffs SUNGENE GMBH & CO., KGAA (DE) 2005-12-22 US disclosed
US-20030180787-A1 Plant 1-deoxy-D-xylulose 5-phosphate synthase CAHOON REBECCA E (US) 2003-09-25 US disclosed
US-6558915-B1 Nucleotide sequences coding polypeptide for use in the generation of isoprenoids in plants E. I. DU PONT DE NEMOURS AND COMPANY 2003-05-06 US disclosed
EP-1135471-A1 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2001-09-26 EP disclosed
EP-1135508-A2 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-26 EP disclosed
WO-2000032792-A9 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE DU PONT (US) 2001-04-19 WO disclosed
WO-2000034448-A1 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-15 WO disclosed
WO-2000032792-A2 PLANT 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-08 WO disclosed